Maximal instantaneous muscular power after prolonged bed rest in humans

Maximal instantaneous muscular power after prolonged bed rest in humans.

A reduction in lower limb cross-sectional area (CSA) occurs after bed rest (BR). This should lead to an equivalent reduction in maximal instantaneous muscular power (W(p)) if the body segments' lengths remain unchanged. W(p) was determined during maximal jumps off both feet on a force platform before and on days 2, 6, 10, 32, and 48 after a 42-day duration BR. CSA of thigh muscles was measured ...

Lung function during and after prolonged head-down bed rest.

We determined the effects of prolonged head-down tilt bed rest (HDT) on lung mechanics and gas exchange. Six subjects were studied in supine and upright postures before (control), during [day 113 (D113)], and after (R + number of days of recovery) 120 days of HDT. Peak expiratory flow (PF) never differed between positions at any time and never differed from controls. Maximal midexpiratory flow ...

Prolonged bed rest in the treatment of the dilated heart.

ALMOST 30 years ago, we began to utilize prolonged bed rest in the treatment of persistent cardiac dilatation and intractable congestive heart failure due to myocardial degeneration. This approach was chosen because of a recognition of the limited efficacy of available therapy. It was applied in selected patients. During subsequent years various theoretic considerations (fig. 1) reinforced our ...

Prolonged bed rest in the treatment of ischemic cardiomyopathy.

Age-related differences in plasma BDNF levels after prolonged bed rest.

Brain-derived neurotrophic factor (BDNF) is a member of the family of neurotrophins and has been implicated in brain resistance to insults. Murine studies have demonstrated increased hippocampal concentration after acute immobilization and decreased concentration after chronic immobilization. In humans, chronic stress and sedentary lifestyle result in decreased plasma BDNF levels, but there no ...